Plaque Assay:
Assay for virus in which a dilute solution of the virus is applied to a culture dish containing a layer of the host cells, convective spread is prevented by making the medium very viscous. After incubation the plaques, areas in which cells have been killed (or transformed), can be recognised and the number of infective virus particles in the original suspension estimated.
Plaque Reduction Assay
a method for titrating an antiserum by analyzing the inhibitory e ect of antibodies on the infectivity of virus using the plaque assay
B.W.J. Mahy, A Dictionary of Virology, Academic Press, 2nd edition, 1997.
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